XyliMelts Clinical Studies and Scientific Reviews

Evaluation of pH Values of Products Managing Xerostomia

Pryanka Tayee, Alexander Hsu, Regina Messer, Scott De Rossi, Katherine Ciarocca, Frederic Rueggeberg, Department of Oral Biology, Augusta University, Augusta GA

The Dental College of Georgia measured the pH of 24 dry mouth products including XyliMelts and reported that, when dissolved, in 5 parts water, XyliMelts has a pH of 8.1. Tayee et al., "Evaluation of pH Values of Products Managing Xerostomia," Dental College of Georgia poster publication, 2015. View Full Study

XyliMelts Time-Release Oral Adhering Discs for Night Time Oral Dryness

J. Burgess, Oral Care Research Associates, and P. Lee, Department of Oral Medicine, University of Washington School of Dentistry

The purpose of this study was to assess whether a self-adhering, slowly-dissolving disc that releases 500mg xylitol, cellulose gum (lubriacnt and humectant), and mild peppermint flavor (XyliMelts for Dry Mouth, OraHealth Corp.) could reduce percieved oral dryness and discomfort while sleeping. View Full Study

OTC Management of Dry Mouth

By Jeff Burgess, DDS MSD, Director-Oral Care Research Associates; Previously Department of Oral Medicine, University of Washington School of Dentistry, USA (Retired)

This article provides an overview of the causes of dry mouth, summarizes how to evaluate the patient with dry mouth, including assessment of subjective complaints and objective measures, lists common dry mouth remedies, and reviews the scientific and supportive product testing literature related to the OTC management of dry mouth. View Full Study

Case Study - Caries reduced and gingival status improved by adhering discs that release xylitol while sleeping (OraCoat XyliMelts)

Charles R Hoeg, DMD, Shoreham New York, and Jeffrey Burgess, Department of Oral Medicine, University of Washington School of Dental Medicine, USA (Retired) present a case where an adult patient used each night while sleeping two OraCoat XyliMelts adhering discs, each disc releasing one-half gram of xylitol over 4-8 hours, and thereby eliminated previously on-going cervical caries. Her gingival and periodontal status improved as well. View Full Study

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