- Clinical Studies for Professionals - OraCoat | XyliMelts
XyliMelts Clinical Studies and Scientific Reviews
Studies On Xerostomia
XyliMelts Time-Release Oral Adhering Discs for Night Time Oral Dryness
J. Burgess, Oral Care Research Associates, and P. Lee, Department of Oral Medicine, University of Washington School of Dentistry
The purpose of this study was to assess whether a self-adhering, slowly-dissolving disc that releases 500mg xylitol, cellulose gum (lubricant and humectant), and mild peppermint flavor (XyliMelts for Dry Mouth, OraHealth Corp.) could reduce perceived oral dryness and discomfort while sleeping. View Full Study
OTC Management of Dry Mouth
Jeff Burgess, DDS MSD, Director-Oral Care Research Associates; Previously Department of Oral Medicine, University of Washington School of Dentistry, USA (Retired)
This article provides an overview of the causes of dry mouth, summarizes how to evaluate the patient with dry mouth, including assessment of subjective complaints and objective measures, lists common dry mouth remedies, and reviews the scientific and supportive product testing literature related to the OTC management of dry mouth. View Full Study
Studies on Plaque Reduction and Caries Control
Case Study - Caries reduced and gingival status improved by adhering discs that release xylitol while sleeping (OraCoat XyliMelts)
Charles R Hoeg, DMD, Shoreham New York, and Jeffrey Burgess, Department of Oral Medicine, University of Washington School of Dental Medicine, USA (Retired) present a case where an adult patient used each night while sleeping two OraCoat XyliMelts adhering discs, each disc releasing one-half gram of xylitol over 4-8 hours, and thereby eliminated previously on-going cervical caries. Her gingival and periodontal status improved as well. View Full Study A published version of this case study is posted at this link: http://www.dentalproductsreport.com/dental/article/case-study-reducing-caries-and-improving-gingival-status-while-sleeping
Effects of A Novel Disc Formulation on Dry Mouth Symptoms and Enamel Remineralization in Patients With Hyposalivation: An In Vivo Study
By Jennifer Ho et al., Beckman Laser Institute, University of California, Irvine, CA.
Researchers at the University of California Irvine studied the effects of OraCoat XyliMelts in the mouths of people with clinically determined dry mouth. View Full Study
Studies on Acid Reflux
Dental Erosion, GERD, and Salivary Stimulation
Jeff Burgess, DDS MSD, Oral Care Research Associates; previously Department of Oral Medicine, University of Washington School of Dentistry, USA (Retired)
This article reports successful results of a controlled trial of XyliMelts and a sweet gel dry mouth remedy for reducing acid reflux while sleeping to reduce all symptoms of gastro-esophageal reflux disease including teeth erosion. View Full Study
Effect on Acid Reflux Symptoms Occurring during Sleep of an Oral Adhering Disc Containing only Food Ingredients
Peter VanderVen et. al.
This study found that using XyliMelts while sleeping significantly reduces acid reflux and heartburn in people with dry mouth. https://www.omicsonline.org/open-access/effect-on-acid-reflux-symptoms-occurring-during-sleep-of-an-oraladhering-disc-containing-only-food-ingredients-2161-069X-1000524.pdf
Studies on pH of Oral Moisturizers
Evaluation of pH Values of Products Managing Xerostomia
Pryanka Tayee, Alexander Hsu, Regina Messer, Scott De Rossi, Katherine Ciarocca, Frederic Rueggeberg, Department of Oral Biology, Augusta University, Augusta GA
The Dental College of Georgia measured the pH of 24 dry mouth products including XyliMelts and reported that, when dissolved, in 5 parts water, XyliMelts has a pH of 8.1. Tayee et al., "Evaluation of pH Values of Products Managing Xerostomia," Dental College of Georgia poster publication, 2015. View Full Study
pH and Erosive Potential of Commonly Used Oral Moisturizers
By Alex J. Delgado DDS, MS et al., Division of Operative Dentistry, Department of Restorative Dentistry, University of Florida, Gainsville, FL.
This study measured the pH values of commonly used oral moisturizers and to evaluate their erosive potential using a gravimetric analysis. View Full Study
Acidic oral moisturizers with pH below 6.7 may be harmful to teeth depending on formulation: a short reportBy Alex J. Delgado DDS, MS et al., Division of Operative Dentistry, Department of Restorative Dentistry, University of Florida, Gainsville, FL. This article describes the risk of tooth erosion from acidic oral moisturizers.