Introduction. Xerostomia (dry mouth or cotton mouth) is caused by many medications, by radiation treatment, by Sjogren’s syndrome, and by airway pressure machines for sleep apnea, with the prevalence increasing with age. In most individuals, daytime dryness can be managed via a number of simple strategies. However, at present there are no products designed to be used at night to reduce the oral dryness perceived upon awakening during the night or in the morning. The purpose of this study was to assess whether a self-adhering, slowly-dissolving disc that time releases 500mg xylitol, cellulose gum (lubricant and humectant), and mild peppermint flavor (Xylimelts for Dry Mouth, OraHealth Corp.) could reduce perceived oral dryness and discomfort while sleeping…

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